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Filtered Search Results
Medchemexpress LLC Amino-PEG4-Boc | 581065-95-4 | 97.0% | C15H31NO6 | 1 G
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Amino-PEG4-Boc is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. This product is a colorless to light yellow liquid.
- Utilized as a PROTAC linker
- PEG-based structure
- Appears as a liquid
- Colorless to light yellow
- Molecular weight: 321.41
- Storage at 4°C, protected from light
- In solvent, store at -80°C for up to 6 months or -20°C for up to 1 month, protected from light
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Medchemexpress LLC NH-bis(C1-PEG1-Boc) | 2171072-53-8 | 99.7% | C17H33NO6 | 100 MG
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NH-bis(C1-PEG1-Boc) is an alkyl/ether-based PROTAC linker, instrumental in the synthesis of Proteolysis Targeting Chimeras (PROTACs). These innovative molecules are designed with two distinct ligands connected by a linker: one targeting an E3 ubiquitin ligase and the other binding to a specific target protein. This mechanism allows PROTACs to effectively harness the intracellular ubiquitin-proteasome system for the selective degradation of target proteins, offering a novel approach in drug discovery and therapeutic development.
- Alkyl/ether-based PROTAC linker
- Used in the synthesis of PROTACs
- Connects E3 ubiquitin ligase and target protein ligands
- Utilizes the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
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Medchemexpress LLC SULT1E1 protein, human, recombinant, N-terminal His tag | >95.0% | 5 UG
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Recombinant human SULT1E1 (estrogen sulfotransferase) expressed in E. coli with an N-terminal His tag. Supplied lyophilized for biochemical and enzymatic assays, the protein sulfates estradiol, estrone, DHEA, pregnenolone, and xenobiotics; the product includes activity data and low endotoxin suitable for in vitro studies.
- Human-derived recombinant protein with N-terminal His tag.
- Supplied amount: 5 μg lyophilized.
- Purity greater than 95% by reducing SDS-PAGE.
- Molecular weight approx. 36 kDa; sequence N2-I294.
- Specific activity 74.44 pmol/min/μg (PAPS → 1-napthol, 37 °C, 20 min).
- Endotoxin <1 EU/μg (LAL).
- Formulated in Tris-HCl, NaCl, and 8% trehalose; 0.22 μm filtered before lyophilization.
- Store at -20 °C; after reconstitution stable at 4 °C for 1 week.
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eMolecules 1314538-55-0 | Potassium N-Boc-aminomethyltrifluoroborate | Combi-Blocks | MFCD19686142 | 237.070 | C6H12BF3KNO2 | 95.000 | [K+].CC(C)(C)OC(=O)NC[B-](F)(F)F | 10g | 267192425
Potassium N-Boc-aminomethyltrifluoroborate | Combi-Blocks | 1314538-55-0 | MFCD19686142 | 237.070 | C6H12BF3KNO2 | 95.000 | [K+].CC(C)(C)OC(=O)NC[B-](F)(F)F | 10g | 267192425
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eMolecules 127828-22-2 | N-Boc-2-(2-aminoethoxy)ethylamine | Accela ChemBio (ASD) | MFCD12031501 | 204.270 | C9H20N2O3 | 97.000 | CC(C)(C)OC(=O)NCCOCCN | 10g | 444754764
N-Boc-2-(2-aminoethoxy)ethylamine | Accela ChemBio (ASD) | 127828-22-2 | MFCD12031501 | 204.270 | C9H20N2O3 | 97.000 | CC(C)(C)OC(=O)NCCOCCN | 10g | 444754764
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Medchemexpress LLC N-Boc-4-piperidinemethanol | 123855-51-6 | MFCD02094488 | 99.9% | 215.29 | 1 ML
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N-Boc-4-piperidinemethanol, also known as tert-butyl 4-(hydroxymethyl)piperidine-1-carboxylate, is a chemical compound with the molecular formula C11H21NO3 and a molecular weight of 215.29. It is commonly used in laboratory settings and has a high purity of 99.91%.
- White to yellow solid appearance.
- Molecular formula C11H21NO3.
- Molecular weight of 215.29.
- Purity (GC) of 99.91%.
- Consistent with structure by 1H NMR Spectrum.
- May cause skin irritation.
- May cause serious eye irritation.
- May cause respiratory irritation.
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Medchemexpress LLC N-Boc-4-bromopiperidine | 180695-79-8 | 264.16 | 25 G
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N-Boc-4-bromopiperidine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
- Appearance: White to light yellow
- Physical state: Solid below 42°C, liquid above 42°C
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Medchemexpress LLC N-Boc-4-hydroxy-L-proline methyl ester | 102195-79-9 | >=98.0% | 245.28 g·mol⁻1 | C11H19NO5 | 25 G
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N-Boc-4-hydroxy-L-proline methyl ester is a Boc-protected hydroxyproline derivative supplied as a research-grade building block used in medicinal chemistry and linker synthesis for ADCs and PROTACs.
- Used as a non-cleavable ADC linker building block
- Suitable for PROTAC linker synthesis
- Boc-protected hydroxyproline methyl ester functional group enables selective transformations
- Provided in gram-scale quantities for synthesis and scale-up
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Medchemexpress LLC Amino-PEG4-Boc | 581065-95-4 | 97.0% | C15H31NO6 | 500 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Amino-PEG4-Boc is a PEG-based PROTAC linker primarily used in the synthesis of PROTACs. These molecules are designed with two ligands connected by a linker, targeting an E3 ubiquitin ligase and a specific protein for degradation via the intracellular ubiquitin-proteasome system. It is a colorless to light yellow liquid with a purity of 97.0% and a molecular weight of 321.41.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Facilitates targeted protein degradation
- Colorless to light yellow liquid appearance
- Purity of 97.0%
- Molecular weight of 321.41 g/mol
- For research use only
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Medchemexpress LLC N,N'-Diferuloylputrescine | 42369-86-8 | 440.49 | 1 MG
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N,N′-Diferuloylputrescine is a pigmentation inhibitor that causes a 57% reduction in pigmentation. It works by significantly reducing the protein level of MITF. Additionally, N,N′-Diferuloylputrescine exhibits strong antioxidant activities by acting as a radical scavenger against reactive oxygen species.
- Inhibitor of pigmentation with 57% reduction
- Significantly reduces the protein level of MITF
- Possesses strong antioxidant activities as a radical scavenger against reactive oxygen species
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eMolecules 68621-88-5 | N-Boc-m-phenylenediamine | Chem-Impex | MFCD06657915 | 208.261 | C11H16N2O2 | 98.000 | CC(C)(C)OC(=O)Nc1cccc(N)c1 | 1g | 449075031
N-Boc-m-phenylenediamine | Chem-Impex | 68621-88-5 | MFCD06657915 | 208.261 | C11H16N2O2 | 98.000 | CC(C)(C)OC(=O)Nc1cccc(N)c1 | 1g | 449075031
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eMolecules 843666-27-3 | Boc-C14-COOH | ChemScene | MFCD23136039 | 342.520 | C20H38O4 | 97.000 | CC(C)(C)OC(=O)CCCCCCCCCCCCCCC(O)=O | 10g | 582644994
Boc-C14-COOH | ChemScene | 843666-27-3 | MFCD23136039 | 342.520 | C20H38O4 | 97.000 | CC(C)(C)OC(=O)CCCCCCCCCCCCCCC(O)=O | 10g | 582644994
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eMolecules 98-80-6 | Phenylboronic acid | Chem-Impex | MFCD00002103 | 121.930 | C6H7BO2 | 99.000 | OB(O)c1ccccc1 | 100g | 112766136
Phenylboronic acid | Chem-Impex | 98-80-6 | MFCD00002103 | 121.930 | C6H7BO2 | 99.000 | OB(O)c1ccccc1 | 100g | 112766136
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eMolecules 850568-54-6 | 4-Boc-phenylboronic Acid | Accela ChemBio (ASD) | MFCD03411946 | 222.050 | C11H15BO4 | 95.000 | CC(C)(C)OC(=O)c1ccc(cc1)B(O)O | 100g | 600821732
4-Boc-phenylboronic Acid | Accela ChemBio (ASD) | 850568-54-6 | MFCD03411946 | 222.050 | C11H15BO4 | 95.000 | CC(C)(C)OC(=O)c1ccc(cc1)B(O)O | 100g | 600821732
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eMolecules 53292-89-0 | Boc-trans-4-aminocyclohexanecarboxylic acid | Ambeed | MFCD01862293 | 243.303 | C12H21NO4 | 98.000 | CC(C)(C)OC(=O)N[C@H]1CC[C@@H](CC1)C(O)=O | 100g | 525066761
Boc-trans-4-aminocyclohexanecarboxylic acid | Ambeed | 53292-89-0 | MFCD01862293 | 243.303 | C12H21NO4 | 98.000 | CC(C)(C)OC(=O)N[C@H]1CC[C@@H](CC1)C(O)=O | 100g | 525066761
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